Fractional Flow Reserve From 3-Dimensional Quantitative Coronary Angiography

Fractional flow reserve from 3-dimensional quantitative coronary angiography: fresh light through an old window.

In this issue of JACC: Cardiovascular Interventions, Tu et al. (1) report on an initial validation study for a less-invasive approach to derive fractional flow reserve (FFR) based on the coronary angiogram. The investigators should be congratulated on developing an innovative means to expand the diagnostic value of angiography by including physiological ischemic assessment, potentially broadeni...

Three Dimensional Quantitative Coronary Angiography Can Detect Reliably Ischemic Coronary Lesions Based on Fractional Flow Reserve

Conventional coronary angiography (CAG) has limitations in evaluating lesions producing ischemia. Three dimensional quantitative coronary angiography (3D-QCA) shows reconstructed images of CAG using computer based algorithm, the Cardio-op B system (Paieon Medical, Rosh Ha'ayin, Israel). The aim of this study was to evaluate whether 3D-QCA can reliably predict ischemia assessed by myocardial fra...

Computed Fractional Flow Reserve (FFTCT) Derived from Coronary CT Angiography

Recent advances in image-based modeling and computational fluid dynamics permit the calculation of coronary artery pressure and flow from typically acquired coronary computed tomography (CT) scans. Computed fractional flow reserve is the ratio of mean coronary artery pressure divided by mean aortic pressure under conditions of simulated maximal coronary hyperemia, thus providing a noninvasive e...

Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study.

OBJECTIVES The aim of this study was to develop a computer model that accurately predicts myocardial fractional flow reserve (FFR) from angiographic images alone, in patients with coronary artery disease. BACKGROUND Percutaneous coronary intervention (PCI) guided by FFR is superior to standard assessment alone. FFR-guided PCI results in improved clinical outcomes, a reduction in the number of...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve